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  • Title: Primary gingival pseudoepitheliomatous hyperplasia with periodontal findings: a rare case report.
    Author: Thorat M, Pradeep AR, Pallavi B.
    Journal: J Periodontol; 2011 Apr; 82(4):652-5. PubMed ID: 21043795.
    Abstract:
    BACKGROUND: This paper is the first-ever report, to our knowledge, of a case of generalized primary gingival pseudoepitheliomatous hyperplasia(PEH) with significant periodontal findings in a 23-year-old Indian female patient. It explains the need to differentiate PEH from squamous cell carcinoma in diagnosis and treatment planning. The present article also reviews current immunohistologic staining methods used to differentiate PEH from squamous cell carcinoma. METHODS: A two-stage surgical approach was used to eliminate the lesion by gingivectomy and gingivoplasty under local anesthesia. Histopathologic examination of excised tissue was done to differentiate it from squamous cell carcinoma. RESULTS: After 1-year follow-up, there was uneventful gingival healing and no recurrence of the lesion. CONCLUSIONS: Differentiation of PEH from squamous cell carcinoma of the gingiva is important for diagnosis and treatment. It is also important to consider PEH as a rare condition of gingival overgrowth.
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