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  • Title: Congenital cutaneous candidiasis associated with respiratory distress in a full-term newborn.
    Author: Tinsa F, Boussetta K, Ben Hassine D, Kharfi M, Bousnina S.
    Journal: Tunis Med; 2010 Nov; 88(11):844-6. PubMed ID: 21049416.
    Abstract:
    BACKGROUND: Congenital candidiasis is rare occurring in most cases in premature and low birth weight new born. It can produce a spectrum of disease ranging from a diffuse skin eruption to a severe systemic disease with or without skin involvement. Amphotericin B is the first-line agent for the treatment of systemic disease. AIM: To describe a congenital candidiasis in a full-term newborn. CASE REPORT: At birth, the newborn had a generalized, erythematous, papulovesicular eruption. He was treated by topic antifungal therapy. However, on the third day, he developed a systemic disease with respiratory distress and fever. Ear, skin swab and gastric aspirate grew to Candida albicans. The newborn was given fluconazole for 10 days with favourable outcome. CONCLUSION: Early topic therapy did not prevent systemic spread of congenital cutaneous candidiasis in our case. Treatment with fluconazole, as the first-line agent, seems effective and safe.
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