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  • Title: 6-Hydroxydopamine lesions of the olfactory tubercle do not alter (+)-amphetamine-conditioned place preference.
    Author: Clarke PB, White NM, Franklin KB.
    Journal: Behav Brain Res; 1990 Jan 01; 36(1-2):185-8. PubMed ID: 2105735.
    Abstract:
    Rats received bilateral infusions of 6-hydroxydopamine into the olfactory tubercle, resulting in a substantial (89%) local depletion of dopamine. This treatment did not significantly alter conditioned place preference produced by (+)-amphetamine, suggesting that the mesolimbic dopaminergic projection to olfactory tubercle does not mediate the rewarding effects of (+)-amphetamine in rats.
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