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  • Title: [51Cr]EDTA intestinal permeability in children with cow's milk intolerance.
    Author: Schrander JJ, Unsalan-Hooyen RW, Forget PP, Jansen J.
    Journal: J Pediatr Gastroenterol Nutr; 1990 Feb; 10(2):189-92. PubMed ID: 2106021.
    Abstract:
    Making use of [51Cr]EDTA as a permeability marker, we measured intestinal permeability in a group of 20 children with proven cow's milk intolerance (CMI), a group of 17 children with similar complaints where CMI was excluded (sick controls), and a group of 12 control children. [51Cr]EDTA test results (mean +/- SD) were 6.85 +/- 3.64%, 3.42 +/- 0.94%, and 2.61 +/- 0.67% in the group with CMI, the sick control, and the control group, respectively. When compared to both control groups, patients with cow's milk intolerance (CMI) showed a significantly increased small bowel permeability. We conclude that the [51Cr]EDTA test can be helpful for the diagnosis of cow's milk intolerance.
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