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  • Title: Cell signaling.
    Author: Iqbal J, Zaidi M, Avadhani NG.
    Journal: Ann N Y Acad Sci; 2010 Nov; 1211():3-8. PubMed ID: 21062291.
    Abstract:
    This review explores advances in our understanding of dynamicism in cellular signaling. Areas highlighted include the role of stochasticity in producing diversity in analogous signaling circumstances; population desynchronization's effect in masking newly appreciated repetitive bursts in protein phosphorylation and messenger RNA production; double-positive feedback interactions and their ability to synchronize multiple signal transduction pathways; scaffolding proteins control over signaling feedback; and frequency-responsive transcriptional regulation as an example of dynamicism in signaling.
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