These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Stereotactic radiotherapy for peripheral lung tumors: a comparison of volumetric modulated arc therapy with 3 other delivery techniques.
    Author: Ong CL, Verbakel WF, Cuijpers JP, Slotman BJ, Lagerwaard FJ, Senan S.
    Journal: Radiother Oncol; 2010 Dec; 97(3):437-42. PubMed ID: 21074878.
    Abstract:
    PURPOSE: Volumetric modulated arc therapy (RapidArc) allows for fast delivery of stereotactic body radiotherapy (SBRT) delivery in stage I lung tumors. We compared dose distributions and delivery times between RapidArc and common delivery techniques in small tumors. METHODS: In 18 patients who completed RapidArc SBRT for tumors measuring <70 cm(3), new treatment plans were generated using non-coplanar 3D conformal fields (conf-SBRT) and dynamic conformal arc radiotherapy (DCA). For 9 patients with tumors adjacent to the chest wall, co-planar intensity-modulated radiotherapy (IMRT) plans were also generated. PTV dose coverage, organs at risk (OAR) doses and treatment delivery times were assessed. RESULTS: RapidArc plans achieved a superior conformity index (CI) and lower V(45 Gy) to chest wall (p<0.05) compared to all other techniques. RapidArc led to a small increase in V(5 Gy) to contralateral lung compared to conf-SBRT (4.4±4% versus 1.2±1.8%, p=0.011). For other OAR, RapidArc and conf-SBRT plans were comparable, and both were superior to DCA plans. Delivery of a 7.5 Gy-fraction required 3.9 min (RapidArc), 11.6 min (conf-SBRT), and 12 min (IMRT). CONCLUSIONS: In stage I lung tumors measuring <70 cm(3), RapidArc plans achieved both the highest dose conformity and shortest delivery times.
    [Abstract] [Full Text] [Related] [New Search]