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Pubmed for Handhelds

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  • Title: The discovery of novel indole-2-carboxamides as cannabinoid CB(1) receptor antagonists.
    Author: Cowley PM, Baker J, Barn DR, Buchanan KI, Carlyle I, Clark JK, Clarkson TR, Deehan M, Edwards D, Goodwin RR, Jaap D, Kiyoi Y, Mort C, Palin R, Prosser A, Walker G, Ward N, Wishart G, Young T.
    Journal: Bioorg Med Chem Lett; 2011 Jan 01; 21(1):497-501. PubMed ID: 21075628.
    Abstract:
    The discovery and structure-activity relationship of a novel series of indole-2-carboxamide antagonists of the cannabinoid CB(1) receptor is disclosed. Compound 26i was found to be a high potency, selective cannabinoid CB(1) antagonist.
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