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  • Title: Late-onset intestinal perforation in the setting of posttransplantation microangiopathy: a case report.
    Author: Aljitawi OS, Rodriguez L, Madan R, Ganguly S, Abhyankar S, McGuirk JP.
    Journal: Transplant Proc; 2010 Nov; 42(9):3892-3. PubMed ID: 21094879.
    Abstract:
    Intestinal perforation in the setting of posttransplantation microangiopathy (TMA) is a very rare event and might be considered a terminal event of intestinal microangiopathy (i-TMA), a rather rarely recognized posttransplantation complication, as it overlaps with the more common intestinal graft-versus-host disease (GVHD). Cases of i-TMA described in literature occurred within with first 100 days posttransplantation or shortly thereafter. In this report, we describe a case of late-onset intestinal perforation that occurred in the setting of systemic microangiopathy more than a year after allogeneic transplantation. In our case, the patient poorly responded to treatment secondary to refractory mircoangiopathy.
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