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  • Title: Novel gemini cationic surfactants based on N, N-dimethyl fatty hydrazide and 1,3-dibromopropane: synthesis, evaluation of surface and antimicrobial properties.
    Author: Badr EE, Kandeel EM, El-Sadek BM.
    Journal: J Oleo Sci; 2010; 59(12):647-52. PubMed ID: 21099142.
    Abstract:
    A fatty hydrazide based cationic gemini surfactants, 1,3-bis (N'-acyl-N,N-dimethylhydrazinium) propane dibromide which possess hydrolyzable amido moieties in the lipophilic portions, were prepared by reacting 1,3-bromopropane with N,N-dimethyl fatty hydrazide. The surface properties were explained and discussed based on the effect of their chemical structures. The micelle-forming ability, foaming ability, and foam stability were evaluated. The prepared surfactants also showed some antimicrobial activity against gram-positive bacteria (Bacillus subtilis, Staphylococcus aureus) but they were not active against gram negative bacteria (Escherichia coli, P. aeruginosa), yeast (Candida albicans), and molds (Aspergillus niger).
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