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  • Title: Seeing is believing: how the MIP-luc mouse can advance the field of islet transplantation and β-cell regeneration.
    Author: Grossman E, Tao J, Wilson R, Park SY, Bell G, Chong A.
    Journal: Islets; 2010; 2(4):261-2. PubMed ID: 21099322.
    Abstract:
    In the last five years, bioluminescence has emerged as a vital tool in the non-invasive quantification of beta-cell mass following islet transplantation in murine models. The successes achieved in bioluminescence imaging in islet transplantation has prompted its use in the discipline of beta-cell regeneration. Employing bioluminescence permits quantifying changes in β-cell mass in an individual mouse over time, which can provide valuable insights into the kinetics of beta-cell regeneration.
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