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  • Title: Neojaponicone A, a bioactive sesquiterpene lactone dimer with an unprecedented carbon skeleton from Inula japonica.
    Author: Qin JJ, Wang LY, Zhu JX, Jin HZ, Fu JJ, Liu XF, Li HL, Zhang WD.
    Journal: Chem Commun (Camb); 2011 Jan 28; 47(4):1222-4. PubMed ID: 21103596.
    Abstract:
    Five new dimeric sesquiterpene lactones, neojaponicone A (1) and japonicones M-P (2-5) were isolated from the aerial part of Inula japonica. Neojaponicone A (1) has an unprecedented carbon skeleton with an unusual valerolactone system formed between a guaianolide and an eudesmane. The structure and absolute configuration of 1 were established by extensive analysis of spectroscopic data and computational approaches.
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