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  • Title: Acute macular neuroretinopathy: contribution of spectral-domain optical coherence tomography and multifocal ERG.
    Author: Maschi C, Schneider-Lise B, Paoli V, Gastaud P.
    Journal: Graefes Arch Clin Exp Ophthalmol; 2011 Jun; 249(6):827-31. PubMed ID: 21103887.
    Abstract:
    BACKGROUND: Acute macular neuroretinopathy is a rare disease which occurs in young women and causes sudden paracentral scotoma and typical reddish-brown macular lesions. MATERIAL AND METHODS: We report two cases of young women suffering from acute macular neuroretinopathy which we observed with spectral-domain Spectralis HRA-OCT and multifocal ERG at 3 and 7 months. RESULTS: Imaging revealed an early hyper-reflectivity of the photoreceptor layer, which changed into hyporeflectivity in the first week and remained the same in the following months, whereas visual field improved. CONCLUSIONS: Our findings show involvement primarly of the outer retina, and confirm OCT and mf ERG as important tools for diagnosis and follow-up of pathologic changes in AMNR, as other diagnostic tests often remain normal.
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