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  • Title: Three new terpenoid indole alkaloids from Catharanthus roseus.
    Author: Wang L, Zhang Y, He HP, Zhang Q, Li SF, Hao XJ.
    Journal: Planta Med; 2011 May; 77(7):754-8. PubMed ID: 21104604.
    Abstract:
    Three new terpenoid indole alkaloids, vidolicine (1), normacusine B N-oxide (2), and lochnerine N-oxide (3), together with seven known ones (4-10), were isolated from whole plants of Catharanthus roseus. Their structures were elucidated by spectroscopic methods (NMR, MS, UV, and IR). Cytotoxic activities of these isolates (1-10) were evaluated, but only compound 8 was active against HL-60, SMMC-7721, and A549 cell lines.
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