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  • Title: Anaphylaxis to benzalkonium chloride-coated central venous catheter.
    Author: Shih CK, Huang SH, Tsai CJ, Chu KS, Wu SH.
    Journal: J Clin Anesth; 2010 Dec; 22(8):632-4. PubMed ID: 21109138.
    Abstract:
    Benzalkonium chloride (BAC) is commonly used as a bactericidal preservative and it may cause allergic reactions in some patients. An unusual case of anaphylactic shock in a 55-year-old woman following insertion of a central venous catheter (CVC) that was coated with BAC is presented. Assuming anaphylactic shock from the CVC, the catheter was removed immediately. Standard resuscitation was started with 100% oxygen, epinephrine, and saline infusion. The patient recovered without any sequelae. One month later, an intradermal skin test was positive for BAC.
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