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Title: Characterization of a G-protein beta-subunit gene from the nematode Caenorhabditis elegans. Author: van der Voorn L, Gebbink M, Plasterk RH, Ploegh HL. Journal: J Mol Biol; 1990 May 05; 213(1):17-26. PubMed ID: 2110981. Abstract: The gene encoding the beta-subunit of guanine nucleotide binding regulatory proteins (G-proteins) has been cloned from the nematode Caenorhabditis elegans. The predicted 340 amino acid sequence matches the highly conserved amino acid sequences of previously isolated G-protein beta-subunits from mammals and Drosophila. The coding region of the C. elegans beta-subunit gene, which has been mapped to the C. elegans chromosome II, is interrupted by eight introns. Southern analysis indicates that C. elegans has only one beta-subunit gene. A 2.8 kb (1 kb = 10(3) bases or base-pairs) transcript derived from this gene could be detected.[Abstract] [Full Text] [Related] [New Search]