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Title: Phenolic compounds from Eucalyptus gomphocephala with potential cytotoxic and antioxidant activities. Author: Al-Sayed E, Martiskainen O, Bobrowska-Hägerstrand M, Sinkkonen J, Törnquist K, Pihlaja K, Ayoub N, Singab AN. Journal: Nat Prod Commun; 2010 Oct; 5(10):1639-42. PubMed ID: 21121264. Abstract: Two new phenolic compounds, 2,4,6-trihydroxy-5-methyl-acetophenone 2-O-beta-D-glucopyranoside (3), and benzyl alcohol 7-O-(3',4',6'-tri-O-galloyl)-beta-D-glucopyranoside (8), together with eight known phenolic compounds, were isolated from the 70% aqueous acetone extract of Eucalyptus gomphocephala DC. (Myrtaceae). The isolated compounds were elucidated based on their 1H, 13C, DQF-COSY, selective 1D-TOCSY, HSQC, and HMBC NMR spectroscopic and ESI-MS data. The antioxidant effect of the phenolic compounds was tested using 1,1-diphenyl-2-picrylhydrazyl (DPPH), hydroxyl radical and super oxide anion radical scavenging assays. The cytotoxicity of the isolated compounds was evaluated using HeLa cell line.[Abstract] [Full Text] [Related] [New Search]