These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Conventional and microwave assisted synthesis of 2-oxo-4-substituted aryl-azetidine derivatives of benzotriazole: a new class of biological compounds.
    Author: Dubey A, Srivastava SK, Srivastava SD.
    Journal: Bioorg Med Chem Lett; 2011 Jan 01; 21(1):569-73. PubMed ID: 21130647.
    Abstract:
    We report herein the synthesis and biological activity of a new kind of azetidinone derivatives of benzotriazole. The reaction was carried out by both conventional and microwave methods. The chemical structures of all the synthesized compounds were deduced according to FTIR, (1)H NMR, (13)C NMR and FAB-mass spectral along with microanalytical data. All the synthesized compounds of series 5a-i were evaluated for their antitubercular activity against Mycobacterium tuberculosis H37RV and antimicrobial activity against some selected microorganism. Unexpectedly, some azetidinone derivatives of benzotriazole displayed better activities.
    [Abstract] [Full Text] [Related] [New Search]