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  • Title: Phenolic metabolites from Pyruscalleryana and evaluation of its free radical scavenging activity.
    Author: Nassar MI, Mohamed TK, El-Toumy SA, Gaara AH, El-Kashak WA, Brouard I, El-Kousy SM.
    Journal: Carbohydr Res; 2011 Jan 03; 346(1):64-7. PubMed ID: 21130983.
    Abstract:
    Investigation of the aqueous alcoholic extract of Pyruscalleryana Decne. leaves led to the isolation of two new phenolic acids glycosides, namely protocatechuoylcalleryanin-3-O-β-glucopyranoside (1) and 3'-hydroxybenzyl-4-hydroxybenzoate-4'-O-β-glucopyranoside (2), together with nine known compounds among them lanceoloside A and methylgallate, which have been isolated for the first time from the genus Pyrus. Structures of the isolated compounds were established by spectroscopic analysis, including UV, IR, HRESI-MS, and 1D/2D NMR. The total extract and some isolated compounds were determined against DPPH (2,2-diphenyl-1-(2,4,6-trinitrophenyl) hydrazinyl radical, for their free radical scavenging activity, the total alcoholic extract showed strong antioxidant activity while the two new compounds showed weak antioxidant activity.
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