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  • Title: Increased potency of an inactivated trivalent polio vaccine with oil-in-water emulsions.
    Author: Baldwin SL, Fox CB, Pallansch MA, Coler RN, Reed SG, Friede M.
    Journal: Vaccine; 2011 Jan 17; 29(4):644-9. PubMed ID: 21134451.
    Abstract:
    The use of inactivated poliovirus vaccines (IPV) will be required to achieve, world-wide eradication of polio. The current expense of IPV is however prohibitive for, some countries, and therefore efforts to decrease the costs of the vaccine are a high, priority. Our results show that the addition of oil-in-water emulsion adjuvants to an, inactivated trivalent poliovirus vaccine are dose-sparing and are capable of enhancing, neutralizing antibody titers in the rat potency model.
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