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  • Title: The role of phospholipase A2 in lipid peroxidation-induced fall of membrane potential of rat liver mitochondria.
    Author: Gogvadze VG, Brustovetsky NN, Zhukova AA.
    Journal: FEBS Lett; 1990 May 21; 264(2):168-70. PubMed ID: 2113483.
    Abstract:
    Cumene hydroperoxide (230 microM)-induced fall of the membrane potential takes place only in Ca2(+)-loaded mitochondria. Inhibitor of phospholipase A2 p-bromphenacyl bromide prevents uncoupling of mitochondria, having no effect on the accumulation of lipid peroxidation products.
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