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  • Title: [Pituitary-testicular evaluation in patients with chronic renal insufficiency in hemodialysis treatment].
    Author: Coppola A, Cuomo G.
    Journal: Minerva Med; 1990 Jun; 81(6):461-4. PubMed ID: 2113639.
    Abstract:
    Hormone assays were performed in 10 nephropathic men on haemodialysis who revealed reduced libido and importance. In particular, testosterone, 17-beta-estradiol, prolactin, FSH and LH plasma levels were assayed in 8 patients before dialysis and at last, after both long and short interdialytic periods. Below normal testosterone, elevated 17-beta-estradiol, FSH at the upper limits of the range and markedly increased LH levels were noticed; prolactin levels were almost normal. No substantial difference was observed between pre- and post-dialytic hormone levels, after either interdialytic periods. Testosterone, 17 beta-estradiol, prolactin, FSH and LH plasma levels were again assayed in 8 patients (six of the former group + two more) and afterwards a test with HCG was performed. Basal hormone levels agreed with the previous ones; prolactin levels were quite normal. An almost complete absence of response of testosterone and 17-beta-estradiol to HCG was noticed. These results demonstrate a primary hypogonadism responsible for reduced libido and impotence in the patients on haemodialysis investigated.
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