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  • Title: [The expressional alterations of CSF-1R after ischemic injury of cerebral cortex].
    Author: Yu DH, Liu S, Tian ZM, Liu SH, Ge XM, Zhou CM, Wang YQ, Fan M.
    Journal: Zhongguo Ying Yong Sheng Li Xue Za Zhi; 2008 Feb; 24(1):6-9. PubMed ID: 21141543.
    Abstract:
    AIM: To observe the expressional alterations of colony stimulating factor-1 receptor (CSF-1R) after ischemic injury of cerebral cortex, and study the function of colony stimulating factor-1 (CSF-1)/CSF-1R signal during the process of ischemic injury and repair of central nervous system (CNS). METHODS: We examined the distribution and expression of CSF-1R in normal brain tissues and ischemic brain tissues by immunohistology and Western blot analysis. RESULTS: The expression of CSF-1R in neurons could be up-regulated by ischemic injury in CNS. CONCLUSION: CSF-1/CSF-1R might take part in the process of ischemic injury and repair.
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