These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Promoter-specific inhibition of transcription by antibiotics which act on DNA gyrase.
    Author: Smith CL, Kubo M, Imamoto F.
    Journal: Nature; 1978 Oct 05; 275(5679):420-3. PubMed ID: 211433.
    Abstract:
    Nalidixic acid, novobiocin and coumermycin specifically inhibit phage promoter-dependent transcription of the trp operon in phi 80 ptrp but not transcription from the authentic trp promoter. The nalidixic acid inhibition is not observed in an E. coli strain containing a nalAr mutation. These results indicate that DNA gyrase is involved in transcription.
    [Abstract] [Full Text] [Related] [New Search]