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  • Title: Increased lysine content in rice grains by over-accumulation of BiP in the endosperm.
    Author: Kawakatsu T, Wang S, Wakasa Y, Takaiwa F.
    Journal: Biosci Biotechnol Biochem; 2010; 74(12):2529-31. PubMed ID: 21150096.
    Abstract:
    Over-accumulation of lysine-rich binding protein (BiP) in the rice endosperm caused strong endoplasmic reticulum (ER) stress and reduced seed storage proteins, resulting in a relative increase in nutritionally balanced non-seed storage proteins. We show that transgenic rice with over-accumulated BiP was a high-lysine rice germplasm and that the over-accumulation of BiP in the endosperm offered a unique strategy to improve the lysine content of cereal grains.
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