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  • Title: Pupil-involving third nerve palsy as a manifestation of anti-myelin-associated glycoprotein neuropathy.
    Author: Tamhankar MA, Galetta SL, Massaro M, Balcer LJ, Stadtmauer EA, Brown MJ.
    Journal: J Neuroophthalmol; 2011 Mar; 31(1):29-33. PubMed ID: 21164358.
    Abstract:
    A 56-year-old man developed a pupil-involving left third nerve palsy. Imaging studies of the brain and intracranial vessels were normal. Neurological examination demonstrated a sensory polyneuropathy and mild distal weakness. Nerve conduction studies showed prolonged distal motor latencies. An enzyme-linked immunosorbent assay test detected high titers of anti-myelin-associated glycoprotein (MAG) antibodies. The patient improved with prednisone and rituximab treatment. Anti-MAG neuropathy should be considered when evaluating a patient with an undiagnosed cranial neuropathy, especially in the setting of a sensory neuropathy.
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