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  • Title: Association between NFKB1 -94ins/delATTG promoter polymorphism and cancer risk: a meta-analysis.
    Author: Zou YF, Yuan FL, Feng XL, Tao JH, Ding N, Pan FM, Wang F.
    Journal: Cancer Invest; 2011 Jan; 29(1):78-85. PubMed ID: 21166501.
    Abstract:
    The aim of our meta-analysis was to assess the association between NFKB1 -94ins/delATTG promoter polymorphism and cancer risk. Eleven studies that included data from 2,743 cases and 2,195 controls were identified. When all groups were pooled, we did not detect the association between NFKB1 -94ins/delATTG promoter polymorphism and cancer risk. In the subgroup analysis, we detected the association of NFKB1 -94ins/delATTG promoter polymorphism with cancer in Caucasian population. The association also was found in Asian population. This meta-analysis demonstrates the association of NFKB1 -94ins/delATTG promoter polymorphism with cancer in Caucasian and Asian populations, and this association is ethno-specific.
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