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  • Title: [Phenomenon of enzymatic imprinting in adult animals].
    Author: Khudoleĭ VV, Mizgirev IV, Maĭorova IG.
    Journal: Biull Eksp Biol Med; 1990 Jun; 109(6):546-8. PubMed ID: 2118814.
    Abstract:
    An inductor of a system of multifunctional monooxygenases, the sovol, being applied to hepatectomized adult rats, produced an enzymatic imprinting, which was expressed in a long-term increase in the aryl hydrocarbon hydroxylase, 7-ethoxycoumarin-deethylase and amidopyrine-N-demethylase activities, as well as in the metabolic activation of benzo (a)-pyrene by the liver S9-fraction in the Salmonella/microsome assay. The phenomena of enzymatic imprinting in adult animals, primarily described, is a reflection of response universality of proliferative cells upon inductors action.
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