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  • Title: Surgery induced immunosuppression.
    Author: Hogan BV, Peter MB, Shenoy HG, Horgan K, Hughes TA.
    Journal: Surgeon; 2011 Feb; 9(1):38-43. PubMed ID: 21195330.
    Abstract:
    Surgery and anaesthesia result in a variety of metabolic and endocrine responses, which result in a generalised state of immunosuppression in the immediate post-operative period. Surgery induced immunosuppression has been implicated in the development of post-operative septic complications and tumour metastasis formation. In addition the effectiveness of many treatments in the adjuvant setting is dependent on a functioning immune system. By understanding the mechanisms contributing to surgery-induced immunosuppression, surgeons may undertake strategies to minimise its effect and reduce potential short-term and long-term consequences to patients.
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