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  • Title: Molecular epidemiology of Plum pox virus in Japan.
    Author: Maejima K, Himeno M, Komatsu K, Takinami Y, Hashimoto M, Takahashi S, Yamaji Y, Oshima K, Namba S.
    Journal: Phytopathology; 2011 May; 101(5):567-74. PubMed ID: 21198358.
    Abstract:
    For a molecular epidemiological study based on complete genome sequences, 37 Plum pox virus (PPV) isolates were collected from the Kanto region in Japan. Pair-wise analyses revealed that all 37 Japanese isolates belong to the PPV-D strain, with low genetic diversity (less than 0.8%). In phylogenetic analysis of the PPV-D strain based on complete nucleotide sequences, the relationships of the PPV-D strain were reconstructed with high resolution: at the global level, the American, Canadian, and Japanese isolates formed their own distinct monophyletic clusters, suggesting that the routes of viral entry into these countries were independent; at the local level, the actual transmission histories of PPV were precisely reconstructed with high bootstrap support. This is the first description of the molecular epidemiology of PPV based on complete genome sequences.
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