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  • Title: [The course of pregnancy in lupus anticoagulant syndrome].
    Author: Spitzer D, Staudach A, Riedl B, Traun H, Steiner H.
    Journal: Geburtshilfe Frauenheilkd; 1990 Aug; 50(8):644-6. PubMed ID: 2120107.
    Abstract:
    More than 95 per cent of the pregnancies with circulating lupus anticoagulant (LA) without therapy lead to abortion or intrauterine death. We report on the course of a pregnancy in a patient, who developed deep venous thrombosis and circulating LA. One of the rare cases of successful pregnancy management without the common prednisolone-aspirin therapy, but with heparin-monotherapy associated with intensive medical and obstetrical surveillance under clinical conditions is reported. In spite of intermittent corticosteroid and immunoglobulin application, a healthy child was born, although normalisation of the aPTT and platelet count was not achieved. It seems, that an alternative concept of therapy may have been established.
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