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  • Title: Adult diagnosis of Swyer-James-MacLeod syndrome: a case report.
    Author: Capela C, Gouveia P, Sousa M, Regadas MJ.
    Journal: J Med Case Rep; 2011 Jan 04; 5():2. PubMed ID: 21205288.
    Abstract:
    INTRODUCTION: Swyer-James-MacLeod syndrome or unilateral hyperlucent lung syndrome is a rare entity associated with postinfectious bronchiolitis obliterans occurring in childhood. It is characterized by hypoplasia and/or agenesis of the pulmonary arteries resulting in pulmonary parenchyma hypoperfusion. CASE PRESENTATION: Here we report the case of a 53-year-old Caucasian woman with Swyer-James-MacLeod syndrome found in the differential diagnosis workup for a new onset of heart failure, secondary to pulmonary arterial hypertension complicated by a patent ductus arteriosus. CONCLUSION: Typically, this disorder is diagnosed in childhood after evaluation for recurrent respiratory infections, but sometimes an indolent course means diagnosis is not made until adulthood.
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