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  • Title: ["Warming yang with pungent and sweet nature" compatibility of Guizhigancao Decoction].
    Author: Lv Y, Gao J.
    Journal: Zhong Yao Cai; 2010 Aug; 33(8):1296-9. PubMed ID: 21213545.
    Abstract:
    OBJECTIVE: To investigate the pharmacodynamic action and the mechanism of the compatibility of "warming yang with pungent and sweet nature" function in Guizhigancao Decoction. METHODS: SD rats were divided randomly into four groups:normal control group, guizhi group, gancao group, and guzhi-gancao group. The function of platelet aggregation and release, the contents of 6-keto-PEG1alpha, TXB, cAMP, cGMP and dissociative calcium ion were detected to verify the effects. RESULTS: Guzhi-gancao group had obvious effects on inducing platelet aggregationby inhibiting ADP, decreasing both wet weight and dry weight of thrombus in vitro, increasing thrombosis and the contents of 6-keto-PEG1alpha and decreasing concentrations of cGMP and calcium ion. CONCLUSION: Compatibility of Guizhigancao Decoction can enhance the function of invigoration pulse beat through "warming yang with pungent and sweet nature".
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