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  • Title: New steroidal alkaloids from Solanum hypomalacophyllum.
    Author: Pérez Colmenares A, Alarcón L, Rojas LB, Mitaine-Offer AC, Pouységu L, Quideau S, Paululat T, Usubillaga A, Lacaille-Dubois MA.
    Journal: Nat Prod Commun; 2010 Nov; 5(11):1743-6. PubMed ID: 21213971.
    Abstract:
    Two new steroidal alkaloids (1-2) have been isolated from the leaves and roots of Solanum hypomalacophyllum Bitter, respectively. Their structures have been elucidated as deacetoxysolaphyllidine-3-O-beta-D-glucopyranoside (1) and 4-keto-5,6-dihydro-(20S)-verazine (2). Furthermore, two known steroidal alkaloids, 20R-verazine and 20S-verazine, and the common secondary metabolites oleanolic acid and beta-sitosterol were isolated from the roots, whereas deacetoxysolaphyllidine was obtained from the leaves.
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