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  • Title: Chemistry and biological activity of essential oils from Piper claussenianum (Piperaceae).
    Author: Marques AM, Barreto AL, Batista EM, Curvelo JA, Velozo LS, Moreira Dde L, Guimarães EF, Soares RM, Kaplan MA.
    Journal: Nat Prod Commun; 2010 Nov; 5(11):1837-40. PubMed ID: 21213995.
    Abstract:
    Analyses of essential oils obtained from fresh and dried leaves and inflorescences of Piper clausenianum were performed using GC-FID, GC-MS and NMR techniques. Forty compounds were detected for these four oils with the total of identified constituents ranging from 88.7% for the dried inflorescences to 97.7% for the dried leaves. Sesquiterpenes were the main constituents in the volatile fraction from leaves with a high percentage of (E)-nerolidol (up to 83%). However, monoterpenes were identified in greater amount in the inflorescences, with linalool percentages from 50% up. The essential oils from fresh leaves and inflorescences were submitted to anti-parasitic activity against a strain of Leishmania amazonensis. Both samples showed biological activity, but the essential oil from P. claussenianum fresh leaves, which was rich in (E)-nerolidol, showed effective growth inhibition of L. amazonensis due to the high percentage of this metabolite in the mixture.
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