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  • Title: Synchronous fluorescence spectrophotometry of benzo[a]pyrene diol epoxide-DNA adducts in workers exposed to polycyclic aromatic hydrocarbons.
    Author: Vähäkangas K, Yrjänheikki E.
    Journal: IARC Sci Publ; 1990; (104):199-204. PubMed ID: 2121646.
    Abstract:
    Synchronous fluorescence spectrophotometry (SFS) for benzo[a]pyrene diol epoxide (BPDE)-DNA adducts detects adducts in lymphocyte DNA in some but not all individuals exposed occupationally to polycyclic aromatic hydrocarbons (PAHs). Individual differences in exposure, activation and/or DNA repair can be detected by SFS. Several in vitro and in vivo studies are currently being done to clarify the specificity and usability of SFS as a biomonitoring method for PAH exposure in the work environment.
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