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  • Title: [Chronic respiratory diseases and atherosclerosis].
    Author: Teramoto S, Akashi S.
    Journal: Nihon Rinsho; 2011 Jan; 69(1):158-62. PubMed ID: 21226277.
    Abstract:
    Chronic respiratory diseases including chronic obstructive pulmonary disease (COPD) are recently recognized as systemic inflammatory disorders and considered to be a new risk factor for atherosclerosis. The increased serum levels of C-reactive protein, TNF, VEGF, IL-6, and ICAM-1 were known in patients with COPD. The accelerated pulse wave velocity(PWV) and the increased intima-media thickness of internal jugular artery were significantly found in the patients, when compared with the smokers without COPD. The anti-atherogenic agents including statins and ARBs are reported to be effective for the reduced mortality in the patients. The possibility of COPD as a novel atherogenic factor is discussed.
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