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  • Title: Age-specific prevalence of herpes simplex viruses in Melbourne.
    Author: Knox J, Redden C, Walton B, Baird R.
    Journal: Pathology; 2011 Jan; 43(1):64-6. PubMed ID: 21240068.
    Abstract:
    AIMS: To characterise the epidemiology of anogenital herpes in Melbourne by detailing the age-specific prevalence of herpes simplex virus (HSV) 1 and HSV 2. METHODS: A cross-sectional study of 2055 anogenital specimens assayed by polymerase chain reaction (PCR) for HSV 1 and 2 at Melbourne Pathology from 1 August 2004 to 11 May 2005 was conducted. Results were analysed by age and sex. RESULTS: PCR demonstrated HSV 1 in 44.1% of all anogenital herpes cases. The relative prevalence of HSV 1 decreased as a function of increasing age. In patients under the age of 20, 18.2% of cases of anogenital herpes were due to HSV 2, as compared with 84.6% in patients over the age of 50. CONCLUSIONS: In this study population a clear relationship is seen between age and relative frequency of HSV 1 and 2 as a cause of anogenital herpes. HSV 2 accounts for only a small proportion of infections in younger patients.
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