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  • Title: Mechanisms of protective effect of Dicarbamin on the blood system in cytostatic treatment.
    Author: Nebolsin VE, Zhdanov VV, Zyuzkov GN, Udut EV, Khrichkova TY, Simanina EV, Stavrova LA, Miroshnichenko LA, Chaikovskiy AV, Dygai AM.
    Journal: Bull Exp Biol Med; 2011 Jan; 150(3):343-7. PubMed ID: 21240350.
    Abstract:
    The effect of Dicarbamin preparation on hemopoiesis suppressed with cyclophosphamide was studied in animal experiments. It was shown that Dicarbamin produced a protective effect on granulocytic hemopoietic steam. This property of the preparation is determined by both protection of immature granulocytic cells at early terms after cytostatic treatment and more active maturation of neutrophils in the bone marrow due to enhanced secretion of humoral factors by elements of hemopoietic environment at late terms of the experiment.
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