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  • Title: [Dependence of sensitization to specific and nonspecific antigens on the individual type of immune reaction in patients with pulmonary tuberculosis].
    Author: Ginda SS.
    Journal: Probl Tuberk; 1990; (9):58-60. PubMed ID: 2125723.
    Abstract:
    Study of cellular sensitization and antibody formation in 317 patients with pulmonary tuberculosis (both concurrent and not concurrent with nonspecific lung diseases) to antigens of M. tuberculosis, staphylococcus, streptococcus and pneumococcus revealed their various interaction in relation to the type of immune reaction. It was noted that with a normergic type of immune reaction, the levels of cellular sensitization and antibody formation to M. tuberculosis antigens were consistent with a hyperergic type, a higher level of cellular sensitization inhibited antibody formation; and with a hypoergic type, the inhibition of cellular sensitization level was accompanied by hyperproduction of antibodies. With an anergic type of immune reaction, inhibition of cellular sensitization and antibody formation to M. tuberculosis antigens was recorded.
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