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  • Title: Comparative studies on semicarbazide-sensitive amine oxidase in heart and plasma of rats treated with hepatotoxin allyl formate.
    Author: Obata T, Yamanaka Y.
    Journal: Int J Biochem; 1990; 22(8):837-9. PubMed ID: 2126247.
    Abstract:
    1. After allyl formate (AF) was administered to the rats, the existence of semicarbazide-sensitive amine oxidase (SSAO) in rat identified. 2. When the heart homogenate and plasma of AF-administered rat were pretreated with 10(-3) M clorgyline and deprenyl, the Km value for benzylamine of rat heart was same as the value of plasma. 3. The existence of SSAO in plasma of AF-administered rats were identified by IEF-gel electrophoresis. The pI values of SSAO in heart and plasma were a single peak of 5.0. 4. SSAO released from the rat heart in response to AF, although the other origins of this enzyme are unknown.
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