These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: One-pot synthesis of luotonin A and its analogues.
    Author: Tseng MC, Chu YW, Tsai HP, Lin CM, Hwang J, Chu YH.
    Journal: Org Lett; 2011 Mar 04; 13(5):920-3. PubMed ID: 21268635.
    Abstract:
    Starting with inexpensive reagents, a self-directed chemical process with the aid of a single metal triflate was readily achieved to concomitantly construct quinazoline and pyrroloquinoline cores to afford the synthesis of luotonin A and its analogues. Among all compounds prepared, 2c, 2d, and 3b exhibit more potent inhibitory activity than luotonin A against human topoisomerase I.
    [Abstract] [Full Text] [Related] [New Search]