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  • Title: Complete regression of melanoma associated with vitiligo.
    Author: Piqué-Duran E, Palacios-Llopis S, Martínez-Martín M, Pérez-Cejudo JA.
    Journal: Dermatol Online J; 2011 Jan 15; 17(1):4. PubMed ID: 21272495.
    Abstract:
    A 53-year-old woman presented with vitiligo. A pigmented lesion was disclosed in the physical examination. Its histopathologic study showed the presence of a band of melanophages in an uneven distribution. Fibroplasia and telangiectasias were also observed, but neither nevus nor melanoma cells were found. A short time afterwards, the patient developed a metastasis in an inguinal lymph node. In spite of high-dose interferon treatment, the patient died two years after the diagnosis. This case associates two uncommon events: a) the whole regression of a melanoma and b) vitiligo associated with melanoma. Although both processes have a similar pathogenic mechanism, this association is exceptional and probably influences the prognosis.
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