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  • Title: Effect of aminoglycoside antibiotics on the autolytic enzyme of Streptomyces griseus.
    Author: Szabó I, Penyige A, Barabás G, Barabás J.
    Journal: Arch Microbiol; 1990; 155(1):99-102. PubMed ID: 2127670.
    Abstract:
    The isolated cell wall of Streptomyces griseus 52-1 strain labelled with fluorescein isothiocyanate (FITC) and containing wall-bound autolytic enzyme was lysed as a function of different cations. The autolysis was accelerated by aminoglycoside antibiotics (streptomycin and the structurally closely related neomycin) which have a polycationic character. Since this strain is a streptomycin producer it is suggested that streptomycin may have a regulatory function on autolysis.
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