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  • Title: Commentary. A picture of Mitf in melanoma immortality.
    Author: Goding CR.
    Journal: Oncogene; 2011 May 19; 30(20):2304-6. PubMed ID: 21278792.
    Abstract:
    The Mitf gene has a key role in melanocytes and melanoma by regulating cell cycle progression, survival and differentiation. Two papers in this issue of Oncogene (Cheli et al., 2011; Strub et al., 2011) reveal that low-Mitf cells can initiate tumors with high efficiency, and that Mitf blocks senescence by regulating genes implicated in S-phase progression and mitosis.
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