These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Rationally designed fluorescence 'turn-on' sensor for Cu2+.
    Author: Ko KC, Wu JS, Kim HJ, Kwon PS, Kim JW, Bartsch RA, Lee JY, Kim JS.
    Journal: Chem Commun (Camb); 2011 Mar 21; 47(11):3165-7. PubMed ID: 21283852.
    Abstract:
    A rationally designed, coumarin-based fluorescent sensor imino-coumarin (IC) displays high selectivity for Cu(2+) over a variety of competing metal ions in aqueous solution with a significant fluorescence increase. DFT/TDDFT calculations support that the fluorescence 'turn-on' of IC originates from blocking the electron transfer of the nitrogen lone pair upon complexation with Cu(2+). IC was successfully applied to microscopic imaging for detection of Cu(2+) in LLC-MK2 cells (in vitro) and several living organs (in vivo).
    [Abstract] [Full Text] [Related] [New Search]