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  • Title: Generalized acanthosis nigricans related to type B insulin resistance syndrome: a case report.
    Author: Jeong KH, Oh SJ, Chon S, Lee MH.
    Journal: Cutis; 2010 Dec; 86(6):299-302. PubMed ID: 21284281.
    Abstract:
    Acanthosis nigricans (AN) is a cutaneous marker for many underlying states such as endocrine abnormality, obesity, certain drugs, and malignancy. Generalized AN is a rare condition and is commonly seen in adults with an underlying malignancy. The type B insulin resistance syndrome, a rare autoimmune disorder, is caused by the autoantibodies to the insulin receptor. Patients typically present with hyperglycemia but also may present with hypoglycemia. We report a rare case of a 36-year-old man with generalized AN and type B insulin resistance syndrome with hypoglycemia.
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