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  • Title: Formyl-methanofuran synthesis in Methanobacterium thermoautotrophicum.
    Author: Bobik TA, DiMarco AA, Wolfe RS.
    Journal: FEMS Microbiol Rev; 1990 Dec; 7(3-4):323-6. PubMed ID: 2128800.
    Abstract:
    The initial step of methanogenesis from CO2 is the formation of formyl-methanofuran (formyl-MFR) from methanofuran (MFR), CO2 and H2. The enzymology of this novel type of CO2 fixation reaction has been difficult to study because formyl-MFR synthesis is subject to a complex activation. Recently, however, a number of advances have made questions regarding formyl-MFR synthesis more approachable.
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