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  • Title: [Participation of phospholipase A2 in uncoupling in rat liver mitochondria induced by products of lipid peroxidation].
    Author: Gogvadze VG, Bruetovetskiĭ NN, Zhukova AA.
    Journal: Biokhimiia; 1990 Dec; 55(12):2195-9. PubMed ID: 2129018.
    Abstract:
    Accumulation of lipid peroxidation products induced by cumol hydroperoxide (230 microM) results in the loss of the membrane potential only in calcium-loaded mitochondria. The phospholipase A2 inhibitor, p-bromophenylacylbromide, prevents mitochondrial uncoupling but has no effect on the accumulation of lipid peroxidation products.
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