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  • Title: [Synaptic localization of 5'-nucleotidase activity in the cerebellar cortex in adult rats irradiated by X rays after birth].
    Author: Bailly Y, Schoen SW, Delhaye-Bouchaud N, Kreutzberg GW, Mariani J.
    Journal: C R Acad Sci III; 1990; 311(13):487-93. PubMed ID: 2129114.
    Abstract:
    5'-nucleotidase cytochemistry was performed in the cerebellum of adult rats exposed previously to a single postnatal X-irradiation which maintains until adulthood the normally transient multiple innervation of cerebellar Purkinje cells by climbing fibers. 5'-nucleotidase activity persists in climbing fiber synapses and other asymmetrical synapses while it is transient during normal development. Therefore, in the X-irradiated rat, an immature stage of the excitatory synapses persists which, for the climbing fibers, coïncides with or precedes their involution during normal development.
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