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  • Title: [Thrombinoscopy: measuring thrombin generation].
    Author: Hemker HC.
    Journal: Ned Tijdschr Geneeskd; 2011; 155():A2572. PubMed ID: 21291579.
    Abstract:
    A test is needed of which the score is low in case of haemorrhagic tendency and high in case of thrombotic tendency. Emerging evidence shows that thrombin generation is a promising candidate. Recently it became possible to measure the course in thrombin concentration in clotting blood or blood plasma in an simple way suitable for application in a routine clinical setting. It appears that the amount of thrombin developing in clotting blood or blood plasma is a better measure for thrombotic- or haemorrhagic tendency than any variant of the clotting time and that thrombin generation is a universal test for the effect of antithrombotic drugs.
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